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The antibody clone H09 is the first commercially available antibody, that specifically stains single cells carrying the IDH1 R132H point mutation in FFPE brain tumor sections.Immunohistochemistry of human IDH1 R132H in standard formalin-fixed paraffin-embedded tissue sections.

The antibody clone H09 is highly useful for brain tumor classification and for the detection of single infiltrating tumor cells.

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Capper et al. (2009) Characterization of R132H mutation-specific IDH1 antibody in brain tumors.

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Noteworthy is the discrimination of the infiltrating edge of tumors with IDH1 mutation from reactive gliosis.German Cancer Research Center (DKFZ) in Heidelberg: Education: Germany: Heidelberg: 7.0: Glendale Community College: Education: United States.